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How tissues take shape - from morphogens to mechanics

Speaker: Prof. Dr. Christian Dahmann, Technische Universität Dresden, Institute for Genetics, Germany
Start: Thursday, February 9, 2023, 6:30 pm
Location: CellNanOs, 38/201

The general interest of our group is to understand the mechanisms by which cells collectively organize to form complex patterns and morphologies in developing tissues. How does collective behavior emerge in cell assemblies? How do mechanical processes like cell adhesion or force generation influence tissue organization? And how are these mechanical processes linked to the chemical signals that orchestrate tissue development? We address these questions by combining genetics with live imaging, quantitative image analysis and biophysical approaches using the fruit fly Drosophila melanogaster as a model organism. Moreover, in collaborations with physicist and mathematicians, we use our quantitative data to build computational models of tissue organization.