Talk by Lena Pernas
Title: "Remodeling of mitochondria during microbial infection"
Occasion: SFB Seminar
Host: Katia Cosentino
Start: 15.06.2023 - 16:15 Uhr
Location: CellNanOs, 38/201
About the speaker: Lena Pernas researches the metabolism of infections at the Max Planck Institute for Biology of Ageing in Cologne.
Abstract of the talk: The rewiring of mitochondrial metabolism serves as an innate immune-type defense mechanism that restricts the growth of the human parasite Toxoplasma gondii. We recently reporteda previously undescribed structure we term SPOT (structure positive for outer mitochondrial membrane (OMM) that emerges from the OMM during infection. We propose that Toxoplasma hijacks the formation of SPOTs, a cellular response to OMM stress, to promote its growth. Here, I discuss the fate and function of these peculiar structures.