Talk by Anant Menon
Dr. Anant Menon
Title: "Lipid scramblases – discovery and mechanism"
Occasion: SFB Special Seminar
Host: Joost Holthuis
Start: 25.05.2022 - 16:15
Location: CellNanOs 38/201
About the speaker: Anant Menon researches the topic "Membrane Biology Structural Biology"at the Weill Cornell Medicine Department of Biochemistry in New York, USA.
Abstract of the talk: Lipids must move rapidly from one side of a membrane bilayer to the other side to grow a membrane bilayer, to signal the engulfment of apoptotic cells by macrophages, and to glycosylate proteins. I will talk about membrane proteins called scramblases that function as channels to facilitate movement of lipids down their transbilayer concentration gradient. I will present (i) unpublished work on the discovery of a scramblase in the mitochondrial outer membrane that is needed for efficient lipid import into mitochondria, and (ii) current ideas about the mechanism of lipid scrambling by the G protein-coupled receptor rhodopsin.